 Adipose-derived stem cells, ASCs, have been shown to possess unique properties such as self-renewal and multipotency, making them an ideal source for tissue engineering. Additionally, they can be obtained from multiple sources and are easier to collect than bone-marrow-derived stem cells, BMSCs. Furthermore, three-dimensional, 3D, tissue engineering scaffolds provide a more realistic microenvironment for ASCs, allowing for improved localization, attachment, proliferation, and differentiation. As a result, tissue-engineered ASCs have become increasingly popular for use in regenerative medicine. This review discusses the characteristics of ASCs, as well as the biomaterials and tissue engineering techniques used to create 3D environments for ASCs. Finally, clinical applications of tissue-engineered ASCs are explored to demonstrate their potential and feasibility in regenerative medicine. This article was authored by RU Dai, Sencha Wang, Roya Samanipore, and others. We are article.tv, links in the description below.