 This paper reports a rare case of a simultaneous co-infection of two types of fungi Rhizopus eryzi and Lomentospora prolificans in a 70-year-old Afghanistanian woman who had been diagnosed with COVID-19. The patient was treated with surgery, Liposomal Amphotericin B, and Voraconazole, and her condition improved significantly after treatment. This is believed to be the first reported case of a co-infection of COVID-19 associated mucormicosis, CAM, and Lomentospora prolificans infection. The authors also review other cases of multiple fungal co-infections in COVID-19 patients. This article was authored by Mazad Arami, Mazad Arami, Hossein Marendi, and others.