 Hello everyone. I'm Dr. Seema Rohira, professor of radio diagnosis, Pundit B.D. Sharma, post-graduate institute of medical sciences, Rotsat Kharayana. Today I'll be talking about hippocampal characteristics among children with calcified neurocystic cirrhosis. NCCS, you know, is one of the most common parasitic infections of the central nervous system in the tropical countries causing epilepsy. The majority of children with NCCS have a well controlled seizure but some have different procedures. In a developing country apart from prolonged federal seizures, NCCS has been considered to be the initial precipitating factor for the development of hippocampal cirrhosis and this dual existence of calcified NCCS and hippocampal cirrhosis is often attributed to a respiratory seizure among children with calcified NCCS. Studies from Brazil have demonstrated that there was a significant association between calcified NCCS and exoleptor hippocampal cirrhosis. It remains an enigma if the association between the calcified NCCS and hippocampal cirrhosis is a mere coincidence or does it indeed have a positive effect relationship. There is positive data on Indian children with calcified neurocystic cirrhosis and has this study was carried out. It was a processional study conducted among children with epilepsy in the age of 14 to 14 years who were diagnosed with calcified NCCS and were attending pediatric neurologic clinic for tertiary care hospital of North India and these children was defined as those who were having two or more unprovoked seizures at least 24 hours apart. The diagnostic criteria for NCCS were as per their brutal phase definition of NCCS. Children with single or multiple calcified seizures through previous radiological scans to give evidence of active NCCS were included in the study. Children with progressive neurological disease, a chronic systemic illness like the chronic seizure of chronic liver disease and those with developmental delay or intellectual disability were excluded from the study. Children with active NCCS were also excluded from the study. Patient information sheet was provided, written information consent taken and aged onset of epilepsy, pregnancy of seizures, seizure of brain interval, doses and anti-hermetic duration was reported. Patient showing evidence of calcified NCCS with prior serial imaging evidence of active NCCS were involved in the study and was subjected to MRI based protocol and EEG. Sleep-deprived electroencephalography recording using 10 to 20 international electoral system was performed. All MRI investigations were performed on 3 Tesla and Mars scanner of GEMate. 31 children were enrolled in total for the study. The total number of calcified legions was studied, concerning the numbers, literality, lower distribution, associated glauces and niolus which were seen as hypo-inducing with an hyperinducing calcification on filter-based images of swan. The calcified NCCS legions were examined for the presence or absence of hippocampus glauces, niotus and periligial glauces. Hippocampus acrophone was considered as borderline if the difference in the volumes of the two-sided hippocampus was 10 to 20% and was considered as definite if this difference in volume was more than 20%. The measurement of hippocampus volume was semi-automated, the outline of hippocampus was placed manually in T plane and once this was done, volume was calculated using this input by ready new software in ADW workstation of GEMate. All the data was entered in Microsoft Excel, IBM, FBXS version 15 and statistical analysis was done. Integral variables were expressed as numbers, that is, person pages and continuous variables were expressed as mean in terms of standard denation or median in terms of intercontinental range. Clinical and radiological features were correlated using SPM and correlation for patient. Out of the total case, 31 cases enrolled, 26 children had well-controlled seizures, one child had moderately controlled seizures and four had poorly controlled seizures. 30 were treated with albendazole for 28 days, majority of them were vegetarian. Among the 31 children with calcium and neurocystereosis, only one child had extra little hippocampus glauces, which was visible. 13 children had either borderline hippocampus acrophone that is 10 to 20% difference in volumes of the two sites or clear hippocampal atrophy that is more than 20% difference. Of these 13 cases of borderline hippocampal atrophy or atrophy, eight had calcified anesthesia on the same site, four had calcified anesthesia on the opposite side and one had calcified anesthesia on both the cells. The hippocampal volume among the enrolled children in the age group of three to six years was 2.84 plus minus 0.16 cubic millimeter and on the right side, and 2.78 plus minus 0.37 cubic millimeter on the left side. Similarly, hippocampal volumes in the age group of 7 to 40 years was 3.1 plus minus 0.8, 5.8 cubic millimeter on the right side and 2.95 plus minus 0.66 cubic millimeter on the left side. Out of six cases of highest percentage asymmetry of hippocampal volumes, four showed more T2 values of hippocampal which were comparatively atrophy. Among 31 children, 27 had nidus within the region and 21 had peregrine cases. There was no correlation between the TGP against the presence of pliocis in the calcified neural sister surfaces. Similarly, there was no significant correlation between the number of calcified regions and absolute hippocampal volumes. There was no correlation of bilateral hippocampal volume with the presence of nidus or pliocis. This is a table showing the TGP of children with calcified anesthesia and here it is showing the number of calcified anesthesia, whether they were single, two, three to five or more than five. And this table shows the correlation between various clinical and universal characteristics among the children with calcified neural sister surfaces. This is a figure of one of the patients which was showing pliocampal apocampal at the left side. This is a CTE image showing calcified lesion in the left area. This is a filter page image of this one showing both the fetus hyperintense and with the hypo-intense nidus within. The hyperintense lesion is the calcified part and the hypo-intense dot within is the scholars. And this is a player image showing the detail of hypo-intensity. These are the images which are showing volumetric. This is the volume of the right-sided hippocampus, which is 2.121 cubic centimetre. And of the left side of the left side of the hippocampus, which is 1.217 centimetre cube showing pliococ left-sided hippocampal atrophy. And this is a clear or bleak T2 weighted coronal image showing the hippocampal atrophy of the left side. The presence study found that 42% of children with C and C had demonstrative hippocampal atrophy. Majority of calcified NCC legions in the presence over triggered nidus in perillegional glances. There was no correlation between the hippocampal volume in the number of calcified legions, presence of perillegional glances or presence of nidus within the legion. Has children with calcified NCCs of perillegional epileptomy focused like hippocampal atrophy in perillegional glances? Hippocampal sclerosis has been reported to be associated with calcified NCC in large number of studies. The presence study showed that only one out of 31 children with calcified NCC had clear evidence of hippocampal sclerosis. It was technically difficult to mediate the existing bongus of the left-facing young children. There is no standard cutoff to define hippocampal atrophy in children as normal and volume-intensive standards that have not been developed. Hippocampal atrophy was defined as the case in which more than 20% of children with calcified NCCs were right in the left side. Using this cutoff, we detected 42% of our children with calcified NCC in the borderline hippocampal sclerosis and up here, that is more than 20% of the difference in the volume of the hippocampal atrophy. In a study from Brazeli, it was found that in patients with calcified NCC, an easier temporal hippocampal sclerosis, the lesion matched the site in which the hippocampal sclerosis observed in 74.1% patients. In our study, out of 13 cases of the hippocampal asymmetry, of 8 hippocampal asymmetry, 8 had existed with sedentary regions, out of which 7 were single lesions. Of the 4 cases, the boundary legions and a couple of the left hippocampals were seen in 3 cases. This could be explained by the fact that the left side did the sedentary hemisphere, the dominant hemisphere and is having more circuitry connections to both the right as well as the left hemisphere. And this also lengths the regions to the theory that in cases of NCC, not only the NCC regions were the patient per se, but some inflammatory process which travels along the circuitry also fair in the development of hippocampal sclerosis. In the 4 cases, the equal number of mediums is right as the left side. The left hippocampal sclerosis, again, may be due to the dominant nature of the left cerebral hemispheres with more connections with the both sides of the brain. The study findings were compared to the Brazilian study. However, in our study, most of the mediums with sedentary hippocampal atrophy were in front of the lateral lobes, unlike the Brazilian study, where 85% were in temporal lobes. Presence of perilegial glauces around the classified NCC has been associated with a higher seizure frequency and seizure of recurrence over 12 months in a period. As 2 cases of our well controlled patients demonstrated perilegial glauces, our study suggested that isolated presence of perilegial glauces cannot be considered as a predictive procedure written around shoulder with classified NCC. The present study had limitations of small sample size, processional study type design, and lack of ACE melch control. In the radiological assessment, T2 relaxometry, which would have had that there is an associated component of mesia and temporal sclerosis, was not performed conceiving the lack of normative age norms for comparison. Moreover, the volumetric mediums of hippocampal were semi-automated, which might be formed from subjective errors and the same is acknowledged. The results of the present study need to be interpreted in the context of this limitation. Further longitudinal studies are recommended with a larger sample size to work for clinical correlation and demolition of hippocampal volumetric victim. We concluded that hippolipidinic focus, like the hippocampal apropyl in perilegial glauces, are prevalent among Indian children with classified NCC. These findings might have implications on the discipline of taking antinatal drugs among well-controlled children with classified NCC services. Further studies with larger sample size and longer follow-up are suggested. So this is a list of preferences which we refer to and thank you very much for your kind attention.