 This study focused on developing a novel hydrogel-based adsorbent for the removal of dichlofenac sodium, DCF, from water. The hydrogel was composed of 1% chitosan, 40% polyethylene glycol-4000, PEG-4000, and 4% santhan gum, CPX. The resulting hydrogel had a high viscosity due to its three-dimensional polymer network and mechanical stability. The physical, chemical, rheological, and pharmacotechnical properties of the synthesized hydrogel were measured. The adsorbent hydrogel showed a high adsorption capacity of 172.41 mg per g at the highest adsorbent amount of 200 mg after 350 minutes. Additionally, the adsorption kinetics were calculated using a pseudo first-order model and Langmuir and Freundlich isotherm parameters. The results suggest that this hydrogel could be used as an effective option for removing DCF from wastewater. This article was authored by Mariana Kellu, Monica Popa, Jose Calderon Moreno, and others. We are article.tv, links in the description below.