 Despite significant health disparities experienced by the lesbian, gay, bisexual, and transgender LGBT population, few investigators associated with the National Institutes of Health, ME, Funded Clinical and Translational Science Award, CTSA, programs are conducting research related to this underserved population. To address this issue, we organized a half-day workshop aimed at increasing researcher readiness to conduct LGBT research. This workshop was presented as part of a series on conducting research with underserved populations offered by the Recruitment, Retention, and Community Engagement, RRC, program of the Center for Clinical and Translational Science at the University of Illinois at Chicago. Six LGBT health research experts provided focused presentations. These presentations included summaries of significant health inequality issues, theoretical models relevant to research on LGBT health, best practices in measuring sexual orientation and gender identity, recommendations for recruitment and retention, discussion of community engagement, and ethical considerations in conducting LGBT research. Based on these presentations, we have compiled a list of recommendations to guide future research, training, and public. This article was offered by Alicia K. Matthews, Kevin Rack, Emily Anderson, and others. We are article.tv, links in the description below.