 Well, good afternoon everybody. Thank you very much for coming. This is a, in my view, quite a special occasion really. It's the celebration of 100 years of the Joel chair and in order to do that we've put together a really special programme. I ought to start really by giving you a few little bits of background to the Joel chair and how it became established. And to do that I've put together a few slides and the slides are really in three columns. The column over this side relates to University College London and University College London Hospital. The column in the middle relates to the Middlesex, the Middlesex Hospital and the Medical School associated with that hospital. And the column over this side, apart from these two images, this column relates to a family whose name is Bonato and they are the reason that we have the Joel chair. In other words they provided the money for the Joel chair and I'll give you a little bit of an explanation about the background to that family. But I wanted to start by just putting a few dates up here and the story really begins in 1745 when the Middlesex Hospital or in fact to give it its true name the Middlesex Infirmary was established in Whitfield Street. They took two houses, they had accommodation for eleven beds of which six were put over to women bearing children so midwifery and they had certain rules applied to that. You have to be married before you could enter the building in order to have your baby. And the other law that was laid down is that they could have no female midwives, only male midwives. The hospital expanded somewhat and moved in ten years to the building which I think most of us would have known, Good Street building which is this picture over here and it then expanded in that building and in 1792 the cancer charity as it was called was established and that meant that the hospital became quite concerned about the way in which cancer treatment was being undertaken in those days. And so it decided it would specialise in that area of cancer treatment. And then in 1835 the hospital had a request to form a medical school. Six senior clinicians decided that they ought to have a medical school and I didn't realise quite what the background was to that particular request was until I looked up a few features about UCL. And UCL was established in 1826 and it formed a hospital in 1834 and you'll notice that date is one year prior to that date. The reason being that the students that wanted to train in medicine were being attracted to UCL and the students therefore were leaving what could have been the potential medical school here because there was no official medical school. So the middle sex corrected that by having its own medical school. So there was some slight conflict between the two departments in those early days. But let me talk a little bit more about this guy who begins to play a role in this story. So here are the two lines for UCL and the middle sex and you'll notice they form into the University of London, part of the University of London in 1900. But down here is a description of the Bonato family, at least a very brief description of them. And they are remarkable in 1871. Two of the brothers in this family went to South Africa with the intention of entertaining the miners because they were people that could sing and dance and so they would go along to the miners' rest areas to sing and dance and entertain the miners. They then noticed that they could also get a little sideline in trading in diamonds. This sideline turned out to be a very large business and in 1888 they sold that business for £5.3 million, a large sum in 1988. They then, with this money, went on and did various things. They became gold miners. They spent their money quite sensibly in a sense. But they did include three members of the family who joined at this point, who were much more lively individuals. One of them became a Bentley boy, in other words, raced at Brooklands and one, several of the races there at Brooklands. Another member of the family raced lots of racehorses, had lots of money gained through that racehorsing business. Eventually in 1906 Harry, the guy that had originally started the diamond business, dies and leaves a large sum of money, £250,000, to the Middlesex Hospital. It's not exactly clear why the Middlesex was chosen, but it's believed that somebody in his family required treatment for cancer and therefore this was a sensible place in which to put the money. In that process, the Middlesex and its medical school built up research labs for cancer development and understanding and also established several chairs, one of which was the Joel chair in medical physics. That was awarded in 1920 to the first Joel chair, Sidney Russ. The following members of that elite club, if you like, of the Joel chair professors is Sidney, who started the business 100 years ago. Eric Roberts, he very much worked with Nobel laureate, Joseph Lopblatt, who in developing an MSc course in radiation physics at that time. James Tate, who came along later, a very important individual scientist in his own right, but his wife and he were both made FRSs on the same day. They are the only couple ever to have done that on the same day. The only married couple to have done it otherwise is Vince Albert and Queen Victoria. Oh no, Davey's shaking his head at me, but I stand corrected on that point. It was quite an important aspect, I think, at that time. Then there was John Clifton, who was there for a short period, followed by Roger and myself currently in that position. I think I've told you enough about the Joel chair and how it's become established and I now wanted to pass you on to the second part of the programme. We're going to have two talks by PhD students and I've asked their supervisors if they would introduce those talks in order to give a couple of minutes background. So I think the first one is going to be Savas and so that means Sandro will give us a couple of minutes introduction to the talk and then Savas might want to come and get his slides ready whilst that introduction is taking place. Thank you.