 So I think that this is another very important question because of course what we are trying to do is to protect the patient and its immediate environment as much as possible. So vaccinating the patient is important but also the vaccination of caregivers and the really close family members is also very important and in fact this is one practice that we have been using for many years in other settings for instance in patients that are stem cell transplantation recipients, one recommendation is to have the family members and the healthcare, the caregivers also vaccinated to try to decrease the possibilities of the patient of being infected. With respect of the, well first of all this practice is not something that we are looking at nowadays with respect to COVID-19 vaccines because apart from the RISC groups then usually in most of the cases people are being vaccinated by age group so this consideration of caregivers and family members being kind of RISC group and having the possibility to being vaccinated earlier this is something which does not exist nowadays at least in Spain. So that's one aspect to take into consideration with respect to the type of vaccine. So here we are talking about a completely different host so the family member or the caregiver can be vaccinated with Pfizer, Moderna, with AstraZeneca, with Janssen so there is not the smallest clear recommendation to use one or the other one basically because we are talking in principle about a healthy person.