 Oxidative stress is a state where the production of reactive oxygen species, ROS, exceeds the body's ability to neutralize them. This can lead to damage to cells, tissues, and organs, and is associated with several chronic diseases including liver and kidney diseases. Antioxidants, such as vitamins C and E, can help reduce oxidative stress by neutralizing ROS before they cause damage. Studies have shown that supplementation with these antioxidants can improve the balance between antioxidant and oxidant levels, potentially slowing down the progression of liver disease. This article was offered by Massoud Amiri.