 Hello everyone, welcome back to another session in dentistry and more today we have an ulcer-like lesion in oral cavity that is necrotizing salometaplasia. So some of the lesions we get the answer from the title itself. So we have three words necrotizing, salo and metaplasia. Necrotizing is nothing but necrosis the death of tissues, it's more like an ulcer lesion and salo means salivary glands and metaplasia is a change of shape. So we have seen hyperplasia, hyperplasia, aplasia, dysplasia. So metaplasia is nothing but it is the beginning of a malignant transformation, the change of shape. So necrotizing salometaplasia is a ulcer-like lesion which is present in the salivary gland. So let's see the details of necrotizing salometaplasia. Necrotizing salometaplasia which is not very common, it is an uncommon local destructive inflammatory condition on the salivary glands. So the cause of this lesion is not known but they believe it as a result of ischemia of the salivary tissue which further leads to local infarction. So ischemia happens which leads to the infarction of the salivary glands. So when there is ischemia, there will not be no blood supply, there will not be no oxygen, the ATP production is lost and there will not be any glucose, it leads to infarction. So what are the predisposing factors? Predisposing factors are traumatic injuries, dental infections, it could be ill-fitting, ventures, upper respiratory tract infections and the adjacent tumors and the previous tumors of the same location. So in some cases, however it may occur without any known predisposing factors. Let's move on to the clinical features. So it most frequently develops in the palatal salivary glands. So that is hard palate is more involved than the soft palate. So the two-third of the cases, okay two-third of the cases that is in palatal they are unilateral. So palatal cases are mostly unilateral with the rest being bilateral or midline in location. So majority of the cases are unilateral and other clinical features it has been reported in others minor salivary gland sites also and occasionally in the parotid gland. Most commonly it is seen in on hard palate but it is also reported in minor salivary glands and also the parotid gland. Whereas a submantibular and sublingual are very rarely affected, submantibular and sublingual, they are very rarely affected by this necrotizing salometoplasia and it is most commonly in adults and the main groups have the prediction over the females. So it appears initially as a non ulcerated swelling and it is mostly associated with pain and parasitia with a crater like ulcer, crater like it is like a depression, okay depression like ulcer which can range from less than 1 centimeter or up to 5 centimeter in diameter and which appears within 2 to 3 weeks. And histopathological features the microscopic appearance of this necrotizing salometoplasia is characterized by a scenar necrosis that is salivary gland, a scenar necrosis in early lesions followed by associated squamous metoplasia of the salivary gland decks. In early lesions the scenar necrosis and further advanced lesion it causes the squamous metoplasia of the salivary decks and the treatment it is basically a self limiting condition and most instances it heals unevenfully without causing any much problems it heals it is a self limiting condition. So that is all about necrotizing salometoplasia it is a ulcer which is seen mainly on the palate that is heart palate due to ischemia and further it is leading to infarction. These are the predisposing factors, traumatic injuries, infictions, ill fitting dentures, upper respiratory tract infection and other tumors heart palate is most involved, adults and men are involved pain and parasitia and most common is a crater like ulcers which is seen within 2 to 3 weeks and there will be very rare chances for submandibular and sublegal gland sometimes it is seen on the minor salivary glands and also parotid glands but mostly heart palate and asinine necrosis and squamous metoplasia of salivary decks in histopathology features and it is a self limiting condition. So that is all about necrotizing salometoplasia it is a short note which has been asking in pathology or pathology. So I will come up with a new topic in the industry and thank you.