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Published on Mar 14, 2016
Table of Contents: 00:00 Homework 3: Sensitivity of Potentiometric Sensors Solutions 03:03 Problem 3.1 Screening of charge on a spherical sensor surface 04:31 SCREENING LIMITED RESPONSE OF BIOSENSORS 06:32 Recall Lecture 3.2: Screening in 1D 09:22 Solution 11:00 Solution 13:06 Salt 15:45 Problem 3.3 Debye length vs. Bjerrum lengths 15:59 SCREENING LIMITED RESPONSE OF BIOSENSORS 20:20 Untitled: Slide 10 20:22 ORIGIN OF CHARGE OF A BIOMOLECULE 21:35 Recall: DNA binding and Salt screening 23:04 ORIGIN OF CHARGE OF A BIOMOLECULE 26:20 ORIGIN OF CHARGE OF A BIOMOLECULE 27:00 Part II: ORIGIN OF CHARGE OF A BIOMOLECULE 27:42 Part II: ORIGIN OF CHARGE OF A BIOMOLECULE 28:03 Part II: ORIGIN OF CHARGE OF A BIOMOLECULE 29:46 BEATING THE SCREENING LIMIT -- SUPERNERNST RESPONSE 30:31 Amplification by a NP-NW Sensors 31:35 BEATING THE SCREENING LIMIT -- SUPERNERNST RESPONSE 33:01 3.7 BiosensorLab pH sensitivity
This video is part of the nanoHUB-U course "Principles of Electronic Nanobiosensors".
This course provides an in-depth analysis of the origin of the extra-ordinary sensitivity, fundamental limits, and operating principles of modern nanobiosensors. The primary focus is the physics of biomolecule detection in terms of three elementary concepts: response time, sensitivity, and selectivity. And, it potentiometric, amperometric, and cantilever-based mass sensors to illustrate the application of these concepts to specific sensor technologies.