 This study examined the causes of interruptions in a hospital pharmacy and assessed the effectiveness of implemented measures for reducing them. It found that interruptions are caused by adaptive behaviors of both pharmacists and nurses, who adjust their workloads to accommodate short staffing and lack of information about the medication dispensing status. To reduce these interruptions, the study introduced measures including a medication dispensing tracking system for nurses, request-based extra medication delivery, and pass boxes for earlier pickup of medications. These measures resulted in a significant reduction in the total number of interruptions, with a 60% decrease in the daily median number of interruptions. This article was authored by Tokahiro Kojima, Noa Yosukinoshita, Harumi Kitamura, and others.