 Our research found that women with osteoarthritis had higher levels of the C-terminal telepeptide of type I collagen, which is a marker for bone resorption, compared to healthy controls. Additionally, we saw a prevalence of bone resorption over bone formation, as well as decreased activity of alkaline phosphatase and osteocalcin, both of which are markers of bone formation. Furthermore, we noticed osteopenia in the spine, which is characterized by a predominantly trabecular type of bone structure. This suggests that osteoarthritis may be associated with osteoporosis. This article was authored by A.S.K. Sinova, A.B. Lepchokova, T.B. Menchakova, and others.