 The Mekong River Basin is a key regional resource in Southeast Asia for sectors that include agriculture, fisheries and electricity production. Climate change could have significant implications for the region's water resources, which are vital for sustaining these sectors. To investigate the potential impacts of climate change on freshwater resources within the river basin, researchers ran pattern-scaled global climate models, GCMs, through a semi- distributed hydrological model, Slurp. They found that the temperature-related signal and discharge was strong enough to overwhelm the precipitation-related uncertainty in the direction of change in discharge, with scenarios from all GCMs leading to increased river flow from April-June and decreased flow from July-August. This article was authored by D.G. Kingston, J.R. Thompson and G. Kite.