 Calendula aficinalis lin. CO, a member of the asteraceae family, has been used for centuries for its medicinal properties. It contains numerous bioactive compounds with diverse biological effects, including anti-inflammatory, anti-cancer, anti-helminthic, anti-diabetic, wound healing, hepatoprotective, and antioxidant activities. Additionally, it is employed in cases of certain burns and gastrointestinal, gynecological, ocular, and skin conditions. Recent research has focused on understanding the molecular mechanisms underlying these effects and exploring potential clinical applications. This review summarizes the current state of knowledge regarding the therapeutic uses of CO and highlights its potential as a traditional medicine. This article was authored by Kiran Shahain, Madhuri Kshirsagar, Srishti Tambi, and others. We are article.tv, links in the description below.