 This research focused on developing magnesium-calcium phosphate bone cements, MCPCs, with zinc added to improve their mechanical and antimicrobial properties. The results showed that the addition of zinc increased the compressive strength of the cement to 48 MPa, while also demonstrating antibacterial activity against both Staphylococcus aureus and Escherichia coli. Additionally, the cement was found to be cytocompatible and could potentially be used as a bone substitute in reconstructive surgery. This article was authored by Paulina A. Crocochiva, Margarita A. Goldberg, Alexander S. Fomin, and others.