 The Dart framework suggests that there are several factors that need to be considered when deciding whether or not to implement new innovations into practice. These include demand, risk, cost, and evolving evidence. By taking these factors into account, organizations can make better decisions regarding which innovations to pursue and how quickly they should move forward with them. Additionally, by forming meaningful partnerships with stakeholders, designing innovations for D&I, and creating a learning health system, organizations can accelerate the translation of innovations into practice. This article was authored by Alex T. Ramsey, Inola K. Proctor, David A. Chambers, and others.