 The study examined the effects of flipped classroom versus traditional classroom on student learning in health professions education. A meta-analysis was conducted on 28 eligible comparative studies which showed an overall significant effect in favor of flipped classrooms over traditional classrooms, standardized mean difference, SMD equals 0.33. The flipped classroom approach was more effective when instructors used quizzes at the start of each in-class session. More respondents reported they preferred flipped to traditional classrooms. The study suggests that the flipped classroom approach in health professions education yields a significant improvement in student learning compared with traditional teaching methods. This article was authored by Kifun HEW and Changkwan LO. We are article.tv, links in the description below.