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Gene variant identified as a heart disease risk factor for women

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Published on Jul 22, 2014

When it comes to heart disease, Dr. Ross Feldman says women are often in the dark. Historically, it was thought that heart disease was a men's-only disease, however, data has shown that post-menopausal women are just as likely as men to get heart disease and are less likely to be adequately diagnosed and treated. New research from Western University published online this week in the British Journal of Pharmacology brings to light a genetic basis for heart disease in women and helps to identify which women are more prone to heart disease.

The study, led by Dr. Feldman, a clinical pharmacologist at London Health Sciences Centre and a researcher at the Schulich School of Medicine & Dentistry's Robarts Research Institute, identifies a common gene variant in women for the G-protein coupled estrogen receptor 30 (GPER) that makes them significantly more likely to have high blood pressure, the single biggest risk factor for heart attack and stroke.

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