 Despite poor descriptions of physical therapy, PT, goals and interventions in neuro-rehabilitation, this study aimed to describe their prevalence in people with neurological disorders, along with clinical features, setting characteristics, and PT impact on outcome measures. A multi-center longitudinal observational study was conducted in Italy, involving hospitals and rehabilitation centers, recruiting 192 participants with stroke, multiple sclerosis, and Parkinson's disease who underwent PT sessions foreseen by the national healthcare system. Results showed that walking was the most relevant PT goal, while interventions aimed at improving cognitive-effective and educational aspects were poorly considered. Considering PT effectiveness, 83 participants experienced a clinically significant improvement in gait and balance functions. This article was authored by Thomas Bowman, Fabiola Jovana Mestanzamados, Sylvia Salvalaggio, and others. We are article.tv, links in the description below.