 The study investigates the safety and efficacy of using Chittos and nanoparticles, CSMPs, loaded with the Iobania vermiculata whole body muscle extract, SE, to treat full skin-induced wounds in rats. SECSNPs showed remarkable antioxidant, anti-inflammatory and antimicrobial activities, reducing oxidative stress, inflammation, and promoting wound healing. The study recommends using SECSNPs to safely treat induced wounds in rats. This article was authored by Alia Farid, at Hamouda, Ahmednabil, and others.