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David O. Morgan (UCSF) Part 3: Controlling the Cell Cycle: Anaphase Onset English Subtitle

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Published on Sep 11, 2011

http://www.ibioseminars.org/lectures/...
In the anaphase stage of the cell cycle, the duplicated chromosomes are pulled apart by a machine called the mitotic spindle, resulting in the distribution of a complete set of chromosomes to each of the daughter cells. In the third part of this lecture, I describe the combination of biochemistry and microscopy in my laboratory that led to the discovery of a regulatory switch that triggers the abrupt and synchronous separation of the chromosomes at the onset of anaphase.

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