 Hi, I am Dr. Sauravashish, consultant urologist in Manipal Hospital, Old Airport Road. Today we will going to discuss about ADPKD. So the full form of the disease is autosomal dominant polycystic kidney cyst disease. It is different from the normal cyst in the kidney because it is hereditary. On the other hand, the other diseases are not hereditary. It means that it can run in the family. The major problem with this disease is that there is no actual treatment available for this problem and only treatment what we can offer to the patient is the early detection and some modification in the lifestyle and the treatment strategies so that kidney failure can be avoided. Up to 30-40% of such patients can lead to renal failure and by having an adequate evaluation and treatment we can delay it and we can avoid renal transplant and dialysis as well. This disease is mainly running with the gene either from the mother or father and whenever it should be suspected whenever there are multiple cysts in both the kidneys as well as there are cyst in the kidney, cyst in the pancreas or in the liver also. Whenever this disease is suspected not only the patient but their sibling as well as parents should also be evaluated with this along with the cyst there are other things which can also give some kind of suspicion of this disease is like early onset of blood pressure, history of cyst in the kidney, history of death in the family because of the renal failure and some history of brain hemorrhage.