 This study found that having knowledge of HIV was strongly associated with consistent condom use among sexually active men in Nigeria. Additionally, educational level, wealth index, and ethnicity were also associated with condom use. These findings suggest that targeted public health interventions should be implemented to increase knowledge of HIV and promote consistent condom use among sexually active men in Nigeria. This article was authored by Obasanjo Afalabi-Bolarinwa, Kobi V. Ajayi, and Rajeeb Kumar Sa.