 Silver nanoparticles, AGNPs, have been recently recognized for their use in agriculture and medicine as antibacterial, antifungal, and antioxidant agents. They bind with biomolecules present in microbial cells, produce reactive oxygen species and free radicals that cause apoptosis leading to cell death, and diffuse into the cell to rapture the cell wall. Smaller nanoparticles are more toxic than bigger ones, and their toxicity is dependent on size, concentration, pH of the medium, and exposure time to pathogens. AGNPs are also used in packaging to prevent damage of food products by pathogens. This article was authored by Kwaja Salahuddin Siddiqui, Azimal Husan, and Rifikat, a.k.a. AO.