 Reporting bias is a common issue in the medical literature, whereby studies are not published if they do not show positive results. This can lead to an overestimation of the effectiveness of certain treatments and an underestimation of their associated risks. To address this issue, mandatory prospective registration of clinical trials should be implemented, along with public access to study data through results databases. This would allow for an independent review of research data, fulfill ethical obligations towards patients, and provide a basis for informed decision making in the healthcare system. This article was authored by Kohl's Heiker, Stullerivorn Beatrice, Christ Julia, and others.