 Fractualated infection, Friday, is a serious medical condition that can cause significant physical and mental distress to patients. It is often difficult to diagnose due to its non-specific symptoms, and it carries a high risk of recurrence if not treated properly. Early diagnosis and appropriate treatment are essential for reducing the risk of infection relapse and disability, as well as improving the patient's quality of life. This article was offered by Tsai Ing-Hee, Bin Yu, and Nan Jiang.