 I'd like to thank the Brain Foundation, the Scientific Advisory Committee and all the donors and sponsors as well. My research interest is on a condition that most of you probably haven't heard of, and it has a really long name. It's called syringomyelia, but it's basically two Greek words that are put together. It comes from the word syrinx, which means tube, and mylos, which means marrow, which refers to the spinal cord. So it's really a condition where you've got fluid-filled cysts in the spinal cord. And as these cysts enlarge, they cause damage to the surrounding spinal cord tissue. And this can cause pain and paralysis. People with traumatic spinal cord injury can develop this. Up to one third of people with a spinal cord injury can develop one of these cysts. And you can imagine that in a person with some disability, but who's relatively independent, how devastating it would be for them to then need to develop further paralysis and need assistance with daily tasks. At the moment, there's only surgery to treat this condition. And it's usually involving a way to release the pressure that the cyst places on the spinal cord. But outcomes from surgery aren't great. And that's in large part because we don't really understand why it forms, why it enlarges. And we don't understand when it does resolve exactly why it doesn't some people, but not in others. And our research group is uniquely placed to try and tackle this problem. I work as part of a collaborative project, which is headed by Professor Stoodley, who's a neurosurgeon, and Professor Lynn Bilston, who's a biomechanical engineer. And our group is made up of engineers and clinicians and scientists like myself. And we meet regularly and we have these really interesting meetings where Professor Stoodley might talk about one of his cases and bring in images of, like, cases of patients before surgery and after surgery. And then we all bring our unique perspective to these cases. The engineers focus on the mechanics and the hydrodynamics of the fluid within the spinal cord. And scientists like myself tend to zoom in on the smaller things and look at what's happening, things that you can't see with a naked eye. And through these discussions we've realized that there's actually a lot of basic things that we don't understand. Everyone here would know that the brain and spinal cord is surrounded by a fluid which we call cerebrospinal fluid or CSF. And we know that it's likely that the CSF is somehow getting into the spinal cord and producing the cyst. But we don't even know the exact anatomical pathways that this fluid moves from the CSF through the tissue to form the cyst. And we don't know the driving forces behind this. And that's what this project is focusing on. It's part of a larger project which will hopefully be funded by the NHNMRC, which uses clinical imaging of patients before and after surgery, computational modelling and lab-based work. And all of these in conjunction we're hoping will lead to better surgical decision-making and in the long run hopefully develop treatments for this condition that don't involve surgery. So thanks again to the Brain Foundation for supporting us.