 Hi, my name is Stefan. I would like to welcome you to our shop floor here in Germany Here in our traditional facility, which is the center of competence for liquid processing We design and manufacture our pharma take product family of pure media process and bioprocess systems Process and packaging is what we do at syndagon The perfect combination of our process technology and our packaging competence Forms the basis for complete production lines for liquid pharmaceuticals In fact from the generation of pure media to the final package products syndagon offers fully integrated solutions from one source Okay, let's talk about this beautiful system behind me This system an SVP 2511 is one of our latest innovations. What does that mean? The SVP product family is a modular platform for configurable liquid process systems These systems are designed for the production of small-volume pharmaceuticals like all kind of small-volume parenterals of talmics, etc The function-based modular concept of the SVP provides our customers with an excellent building set To transfer the best of production requirements to flexible reliable and future-oriented process systems the ergonomic and hygienic design with the Integrated clean room wall and the ceiling completes the package of the SVP interested Let me invite you to discuss your recipes and process requirements. I'm sure that we have the right answer for you SVP the perfect match for every batch Syndagons model SVP process system is a highly modular and flexible solution for the production of small-volume pharmaceuticals It features a pre-fabricated integrated clean room design with all paraffile technology outside a clean room in a technical skid The production area itself can also be separated and run under different room classifications as required by the application The highest degree of flexibility is provided in both the layout of the customer's room concept and the configuration of the production units themselves Syndagons and the customer jointly define the shape, volume and functionality of up to five fixed or mobile vessels And we thereby deliver exactly the formulation system the customer needs for his products Over 70 pre-tested functional modules are available to process batch sizes from 13 to 3,000 liters offering incredible flexibility and convenience From the optional mobile homogenizer to the integrated CIP module Everything is available The pre-fabricated integrated clean room design includes the laminar flow and lighting units And since the safety of the operators and products comes first We can meet complex requirements such as the septic processing or the handling of toxic substances simply by including the appropriate functional modules Our automation architecture, which is structured according to ISA 88 is one of the foundations of our modularization concept Mechanics electronics and software merged into intelligent mechatronic modules in our systems The implementation of our individual recipes on the SVP process system can be realized in three different ways Program production and batch management sequences We strive to define trends and drive digital production The result attractive solutions for production, monitoring and control The SVP has your current and future small-volume pharmaceutical formulation needs covered Interested in learning more? Let's have a closer look Okay, here we are Let's start with the operator's workstation The central position on the platform enables easy economic access to all process vessels The sterile filtration units and substance addition Also very important is the automation interface HMI all is available within an arm's length Our intention the operator is always in the center of action Do you know the facts and figures on the SVP platform? It's interesting Let me briefly list the key facts for you before we move on with our tour Batch sizes between 13 and 3000 liter up to five vessels mobile or fixed design Extremely wide production ranges due to special vessel shapes fully integrated interface to syndicon fitting lines And this is possible with our available 70 functional modules with more 400 varieties And last not least our high-end automation system After having the key facts in mind Let's move on to one of the most important steps in the formulation process the addition of substances and APIs Besides further multiple options APIs and Excipients can be basically added by manual addition via the hand hole under laminar flow coverage Let me tell you in this context that the laminar flow units are fully integrated in our SVP platform as well as the ceiling and the clean room wall Okay, coming back to the substance addition For larger amounts or critical substances many further options like vacuum conveyors Liquid dosing stations or containment solutions for toxic or sterile substances are available and the good news Everything's comes out of the box What's next? Considering the diversity of products and their pharmaceutical forms each product must be treated in different ways Solutions suspensions or emulsions. We know the right way to mix and homogenize the product is important for the quality The SVP offers a wide range of options from low to high shear mixers to high performance Homogenizer and emulsifiers to vibration mixers reach reach your product as required By your burden reduction sterile filtration or septic processing not a problem with the SVP Our integrated sterile filter station comes with a wide range of sizes all optimized to minimize product loss Independent CRP SRP the possibility for product recovery and the integrated filter test Provides the highest level of safety and flexibility Out of sight out of mind not with the SVP What about all the parts of the equipment which are very important for the process but not necessary to have in the clean room? The SVP provides a technical area well designed for accessibility for maintenance Starting with the clean utilities to the gas and temperature control units To the automation system cabinets all are located in the segregated area with easy convenient access for maintenance and Importantly significantly lower operating costs If the mines not strong the body acts weak even when it's not So let's wrap up with a look at the automation system The system operators will find a user-friendly interface that provides a comprehensive overview of all processes running in real time Starting with the navigation screen the operator always has a link to the individual sections for monitoring and configuration Overview screens for the entire system and each functional unit like the formulation vessel always provide a status of the process and the process related values Besides facilitating the fully automated operation the system provides many features to monitor or analyze the processes All results are documented in reports event histories and audit trail Different products and processes require different level of flexibility Your production recipes can be handled in different ways and provide a level of flexibility required by each use case From flexible and individually selectable functions to master recipes To high-end recipe management systems the SVP automation system provides you with the flexibility you need For your future oriented and highly flexible production Our recipe management system provides you with the opportunity to configure new recipes out of a function-based phase library The SVP with its powerful automation system Represents state-of-the-art technology and syndicons orientation to the future It is your companion for success Thank you for your interest in our process technology The SVP process system and our entire pharma tech process solutions are part of syndicons comprehensive pharmaceutical equipment portfolio From clean utilities to formulation filling inspection and secondary packaging Syndicon is your one-stop shop for pharmaceutical process and packaging equipment and services If you have any further questions, please contact us for further informations We invite you to view our additional technology video presentations and look forward to hearing from you Thank you again and talk to you soon