 The present study describes the development and evaluation of a novel biocompatible dendrimer-based nanodrug delivery system that efficiently encapsulates protoporphin-9, PP, a hydrophobic photodynamic therapy, PDT, agent, and reduces its toxicity when compared to free PP without light treatment. Treatment of Dalton lymphoma acides, DLA, cells with the PGSA dendrimer formulation in combination with light resulted in significant enhancement in therapeutic efficacy of PP. This article was authored by Murugasan Suresh Kumar, Anish Babu, Ramachandran Murugasan, and others.