 Serium oxide nanoparticles, so NPs, possess antioxidant properties both in vitro and in vivo, as they can regenerate their surface in response to their environment. They also contain oxygen vacancies in the lattice structure, allowing them to switch between CO2 and CO2-X states during redox reactions. These nanoparticles have been widely researched for their potential use in treating diseases characterized by high levels of reactive oxygen species, ROS, such as cancer. Recent studies have shown that so NPs can mimic enzymes and scavenge ROS, suggesting their potential use in personalized medicine. This article was authored by Atul Dahl and William Self.