 Polypharmacy is common among older adults, with many requiring multiple medications to treat their conditions. This can lead to increased risks of adverse drug reactions and drug-drug interactions, DDIs, which must be carefully monitored. In this study, researchers evaluated the prescriptions of 259 elderly patients attending a hospital in Saudi Arabia over a five-year period. They found that 97.2% of these patients were on multiple medications, with 85.3% having at least one potential DDI. The most frequent type of DDI was between clopidogrel and esomeprosal, which was found in 18% of patients. Additionally, 12% of patients had a DDI between anoxaparin and aspirin, which requires therapeutic modification. These findings highlight the importance of careful monitoring of polypharmacy in elderly patients, as well as the need for clinicians to identify and address potential DDIs. This article was authored by Riam M. Alamedi, Ghaziae Bamegas, Safa M. Alsinosae, and others. We are article.tv, links in the description below.