 This study compared the bone incorporation and remodeling processes of xenogenic and blocked grafts placed using two bone grafting techniques, on-lie versus inlay, in rabbits. The results showed that the percentage of new bone increased faster and was higher in the inlay grafts than in the on-lie grafts, likely due to the self-contained conformation of the recipient site in the inlay group. The osteoconductive properties of the biomaterial allowed the newly formed bone to reach the most peripheral regions in both groups, and the collagen membrane protected the defects from infection and allowed marginal closure by newly formed bone in the inlay group. This article was authored by Raiuchi Sakabuchi, Samuel Porfirio Xavier, Kenzo Morinaga, and others.