 Our study suggests that maternal vaccination against club zeolinumonia could significantly reduce the global burden of neonatal sepsis due to this pathogen. Our analysis indicates that maternal vaccination could avert up to 80,258 neonatal deaths and 399,015 neonatal sepsis cases per year worldwide, representing approximately 3.4% of all neonatal deaths. This would be particularly beneficial in sub-Saharan African countries like Sierra Leone, Mali and Niger, where the vaccine could potentially avert over 6% of all neonatal deaths. This article was authored by Chirag K. Kumar, Kristi Sands, Timothy R. Walsh and others.