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Published on May 25, 2016
Glyphosate is the active ingredient in the pervasive herbicide, Roundup. Glyphosate's inventor, Monsanto, has assured us that glyphosate is nearly nontoxic to humans. This is blatantly untrue. Glyphosate's toxicity is insidious, and it comes about mainly because glyphosate is a synthetic amino acid. Amino acids are the building blocks of proteins. When you replace glycine, an amino acid, with glyphosate, a synthetic amino acid, in a protein, often the protein no longer works as intended. Sometimes it can't be broken down and it accumulates in the brain, causing neurological disease. Other times, it is inactivated as an enzyme or it can't attach to a membrane. Glyphosate also pretends to be glycine at glycine receptors. Glycine is a neurotransmitter, but glyphosate fools the receptor and then doesn't behave as expected. This wreaks havoc on human physiology in multiple ways, leading to a nearly complete explanation for the strong correlations between the rise in glyphosate usage on crops and the increased incidence in a host of chronic modern diseases, including diabetes, obesity, Alzheimer's disease, Parkinson's disease, ALS, adrenal insufficiency, anemia, spina bifida and autism. In this talk, I will try to keep the scientific jargon as simple as possible, while presenting an amazing story about biochemistry gone awry.