 During the past 25 years, an increase in the prevalence of methicillin-resistant staphylococcus aureus, HMRSA, has been recorded worldwide. Additionally, MRSA infections may occur outside and independent of hospitals, caused by community-associated MRSA, CAMRSA. In Germany, it was found that at least 10% of sporadic infections are due to livestock associated MRSA, LAMRSA, which is initially associated with livestock. The majority of these MRSA cases are attributed to clonal complex CC398. LAMRSA CC398 colonizes the animals asymptomatically in about half of conventional pig farms. For about 77% to 86% of humans with occupational exposure to pigs, nasal carriage has been reported, it can be lost when exposure is interrupted. Among family members living at the same farms, only 4% to 5% are colonized. Spread beyond this group of people is less frequent. The prevalence of LAMRSA in livestock seems to be influenced by farm size, farming systems, usage of disinfectants, and infeed zinc. LAMRSA CC398 is able to cause the same kind of infections in humans as S. aureus and MRSA in general. It can be introduced to hospitals and cause no sacomial infections such as postoperative surgical site infections, ventilator-associated pneumonia, septicemia, and infections after joint replacement. For this reason, screening for MRSA colonization at hospital admittance is recommended for farmers and veterinarians with livestock contacts. Intra-hospital dissemination, typical for HMRSA in the absence of sufficient hygiene, has only rarely been observed for LAMRSA to date. The proportion of LAMRSA among all MRR. This article was authored by Christian Cuny, Lothar H. Wheeler, and Wolf Gangwet. We are article.tv, links in the description below.