 This paper provides a comprehensive review of the current research on botanical drugs and their potential role in treating glycolipid metabolic diseases. It discusses how botanical drugs can regulate reactive oxygen species, ROS, and its impact on glucose and lipid metabolism. It also highlights the importance of understanding the mechanisms behind the regulation of ROS by botanical drugs and the potential implications for the treatment of glycolipid metabolic diseases. This article was authored by Maokai Luo, Yu Hongzhen, Shuyun Tang, and others.