 This study investigated the relationship between plasma and urinary levels of tumor necrosis factor alpha, TNF alpha, and chronic kidney disease, CKD, in patients with type 2 diabetes mellitus. The results showed that there was no significant difference in the plasma level of TNF alpha between patients with different stages of CKD. However, the urinary level of TNF alpha increased significantly with increasing severity of CKD. Therefore, it can be concluded that the plasma and urinary levels of TNF alpha are related to each other, and that the urinary level of TNF alpha may be used as a biomarker for monitoring the progression of CKD in patients with type 2 diabetes mellitus. This article was authored by Ali Reza Soleimani, Miriam Soleimani, Foras Farzanijad, and others. We are article.tv, links in the description below.