 This study investigated the effects of cisplatin on rats over a period of three days. It found that cisplatin caused significant damage to the kidneys and liver, with symptoms becoming more pronounced over time. Cisplatin also affected several biomarkers, including blood urea nitrogen, creatinine, and serum nitrites, which all increased over time. Additionally, it was noted that cisplatin decreased the levels of alkaline phosphatase and alanine aminotransferase, but increased the levels of aspartate aminotransferase. This suggests that cisplatin has a negative effect on the liver and kidneys, and can cause serious damage if administered too soon or for too long. This article was authored by Zara Pazeski, Atusa Kasravi, Mina Nakiai, and others.