 Over the last decade, more than 5,000 papers have been published about TOR, an enzyme inhibited by the drug Rappomycin, a drug used experimentally to extend lifespan, but already in use clinically to prevent the rejection of kidney transplants. Patients who received Rappomycin due to kidney transplantation had a peculiar side effect— a decrease in cancer incidents. In a set of 15 patients who had biopsy-proven Kaposi sarcoma, a cancer that often affects a skin, within three months, after starting Rappomycin therapy, all cutaneous Kaposi sarcoma lesions had disappeared in all patients. This makes sense given that TOR functions as a master regulator of cellular growth and proliferation. For example, TOR is upregulated in nearly 100% of advanced human prostate cancers. Maybe that's why dairy consumption has been found to be a major dietary risk factor. We used to think it was just all the hormones in milk, but maybe prostate cancer initiation progression is also promoted by cow's milk stimulation of TOR. Our understanding of mammalian milk has changed from a quote-unquote simple food to a species-specific endocrine signaling system, which activates TOR, promotes cell growth and proliferation, and suppresses our body's internal house-cleaning mechanisms. Now, normally, milk-mediated TOR stimulation is restricted only to infancy, where we really need that constant signal to our cells to grow and divide. From an evolutionary perspective, it can be concluded that the persistent abuse of the growth-promoting signaling system of bovine milk by drinking milk over our entire lifespan maintains the most important hallmark of cancer biology, sustained proliferative signaling. Grow, grow, grow. TOR appears to play a role in breast cancer, too. A higher TOR expression has been noted in breast cancer tumors and associated with more aggressive disease and lower survival rate among breast cancer patients. This could explain why women hospitalized for anorexia may end up with only half the risk of breast cancer. Severe caloric restriction in humans make them for protection against invasive breast cancer by suppressing TOR activation. But we don't have to starve ourselves to suppress TOR. Just reducing animal protein intake can attenuate overall TOR activity. Moreover, plants emphasizing plants, especially cruciferous vegetables, not only decrease TOR activation, they also provide natural plant-derived inhibitors of TOR in broccoli, in green tea, in soy, in turmeric, in grapes, along with other fruits and vegetables, such as onions, strawberries, blueberries, mangoes, and the skin of cucumbers. Maybe that's why plant-based diets are associated with lower risk for many cancers that down regulation of TOR. So are we finally on the threshold of being able to fundamentally alter human aging and age-related disease? Only time will tell, but if the pace and direction of recent progress are any indication, the next 5,000 studies on TOR should prove very interesting indeed.