 coronavirus disease 2019, COVID-19, causes high morbidity and mortality in long-term care facilities, LTCFs. COVID-19 vaccine effectiveness against infection was 81.5 percent and 81.4 percent among fully vaccinated residents and staff in LTCFs. The vaccine effectiveness against COVID-19 associated death was 93.1 percent among residents and no hospitalizations occurred among fully vaccinated staff. This article was authored by Jostein Staffelt and Eskaira Danielsen, Oliver Kasselnick and others.