 The Texas Community Engagement Alliance consortium was formed to address the disproportionate impact of COVID-19 on underserved minority populations in five counties in Texas. The consortium has partnered with local organizations and institutions to develop community-engaged projects aimed at reducing the spread of the virus and providing access to clinical trials and vaccines. This article was authored by Rebecca A. Seguin Fowler, Chris Amos, Bettina M. Bitt and others.