 Hello, my name is Ernesto Rodan Valadez, I am a diagnostic radiologist and clinical investigator at the MRI unit of Medica Sur Clinic and Foundation. Hi, my name is Jesus Martínez Sander, I am a senior resident of neurosurgery at the National Institute of Neurology and neurosurgery at Mexico City, and I am a professor of anatomy at the National University of Mexico. Hi, my name is Dr. Roberto Poronatedillo, neurobiologist at Medica Sur Clinic and Foundation. We would like to invite you to read our review paper about cranial nerves. We suspect that in their early years some medical students and residents avoid the difficulties of cranial nerves because of their complex anatomy. However, there is a broad community of health science professionals interested in the anatomy of cranial nerves. There are specialists in neurology, neurosurgery, radiology, otolaryngology, oftalmology, maxillofacial surgery, radiation oncology and emergency medicine. And also related fields, nurses, physician assistants, students and practitioners of dentistry, pathology, audiology, physical and health education and rehabilitation science. During the last two decades advances in neuroimaging using high resolution computer tomography and magnetic resonance imaging have enabled to brain structures to be visualized in highly detailed ways that now enable normal findings and nervous system pathology to be detected in a day to day basis. In this manuscript we integrate the perspectives of radiologists and neurosurgeons to provide a practical imaging review combining the use of 128 slice dual source multi-panel images from CT systemography with 3T MRI. For each cranial nerve we present information regarding origin, course, function and a brief listing of the most common pathologies and syndromes affecting them. In view of the copies available data about these structures the scope of this article is focused on clinical anatomy and readers will find specialist texts presenting more detailed information about particular topics. The final goal of our manuscript is to provide helpful reference to understanding the complex anatomy of the cranial nerves.