http://drcharlesparker.com - Learn more about how your medications are expected to perform. This knowledge helps guide your treatment success; you will better understand if your medications are working correctly.
To see the connection between brain science and common sense: evidence matters.
Details Matter: The Meds Don't Work Long Enough: The Duration of Effectiveness [DOE] is not adequate: Each stimulant drug, each family of stimulant drugs has its own expected DOE. This DOE is not discussed in the literature as a measuring tool, but it's common knowledge with any who watch carefully for drug action and duration through the day.
All stimulant medications have an expected, less than 24 hr duration.This is an obvious point, but overlooked so often as an essential tool. If meds last less than 24 hr, then how long should each last? Dialing in the specific duration is essential to get the best action out of each specific med. [AMP=Amphetamine Family, MPH=Methylphenidate Family]
Vyvanse [AMP] and Daytrana [MPH patch] both win the DOE race with 12-14 hr expected
Adderall XR [AMP] is next with 10 hr DOE -- sometimes can get 12, but often 12 DOE is too much
Concerta [MPH] and Focalin [MPH] both run 8-10 hr if dialed-in effectively - some studies show longer, my experience: more than 10 hr with either of these is too much -- see other articles on the 'Top of the Window'
Metadate CR [MPH] and Ritalin LA [MPH] are both right at 8 hr, rarely longer, with side effects if pushing the dose higher
The Immediate Release Stimulants, the tablets with no extended time expected, last only a portion of the day with Adderall IR [AMP] [Immediate Release Tabs] lasting about 5-6 hr, Ritalin IR [MPH] is 4 hour max duration.
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