 On February 17, 2021, St. Lucia, through the Ministry of Health and Wellness, launched the National COVID-19 Vaccination Campaign. This campaign is now in its sixth week of implementation, and as of Monday, March 29, 2021, a total of 22,011 individuals have received the first of two doses of the Oxford AstraZeneca vaccine. Amongst these individuals are health sector professionals, officials within national security, border protection, tourism sectors, as well as various staff within line ministries. Vaccines have also been received by our senior citizens, people living with mobility challenges, and individuals living with lifelong chronic illnesses, all of whom are at particularly high risk for the severe COVID-19 illness, if infected by the virus. This significant response to the national campaign has resulted in our initial stock of 23,000 doses of COVID-19 vaccines being augmented by St. Vincent and the Grenadines, which loaned us an additional 5,000 doses to allow for the completion of our phase one of our national vaccine campaign. Early in April 2021, St. Lucia expects the first shipment of 24,000 doses of the Oxford AstraZeneca vaccine from the COVAX facility. These doses shall be used to commence phase two of the campaign and to administer the first batch of second doses of the AstraZeneca vaccine. Initially, St. Lucia had decided on a six-week interval for receiving the second vaccine dose. However, the World Health Organization, in its last release on March 16, 2021, noted that a wider second dose interval of 8 to 12 weeks is recommended. This revision was done as it has been proven that this wider window increases the effectiveness of the vaccine as it provides increased protection from the virus to individuals who are vaccinated within this updated schedule. Considering this update, the Ministry of Health took the decision to reschedule the second dose appointment to eight weeks for people who were initially given the six-week appointment after the first dose. The Ministry of Health will be informing these individuals of the new date of the second COVID-19 vaccine dose by way of a phone call or through the management of their organizations. Like any other vaccine or medication, there are common side effects associated with these products which some people may experience. For the COVID-19 vaccine, these side effects are generally mild to moderate. When they do occur, they tend to last about 24 to 48 hours after receiving the vaccine. Common reported side effects include tenderness, pain, warmth, and or swelling at the injection site, fever, chills, fatigue, headache, nausea, muscle ache, and body pains. There have been few reports of rash, bleeding, dizziness, sweating, and abdominal pains. The Ministry of Health is encouraging people who experience side effects associated with the vaccine to report this to the healthcare provider. This is part of the monitoring and evaluation process of the COVID-19 vaccination program. To date, there is no evidence of death caused by Oxford AstraZeneca vaccine globally, nor in St. Lucia by the Ministry of Health. The vaccine has been manufactured in keeping with the strictest safety requirements from the stage of manufacturing to the administering of the vaccine to individuals and the monitoring which follows vaccination. The COVID-19 vaccine is safe, it is free, and is being made accessible to all over the age of 18 years. The Ministry of Health will be providing further updates on the COVID-19 vaccination campaign in the coming week.