 The study investigates the effect of different intensities of electroconvulsive seizures, ECS, on antidepressant-like responses and hippocampal neurogenesis in female rats, with adolescents and adulthood being evaluated. It found that lower intensities of ECS were effective in adult females but not in adolescent ones and that the characteristics of the induced seizures differed between age groups. Additionally, the study suggests that other molecular mechanisms may be involved in the antidepressant-like effect of ECS beyond hippocampal neurogenesis. This article was authored by Sandra Le Desmakovay and M. Julia Garcia-Fuster.