 This study found that patients with chronic pylonephritis and colisostitis who had been diagnosed with a quantitative qualitative blood pressure cluster had a distinctive immune profile. This included elevated levels of interleukin, six- and tumor necrosis factor alpha in the blood, increased activity and intensity of phagocytosis by neutrophils of staphylococcus aureus and higher concentrations of certain immunoglobulins in the serum. These findings suggest that the immune system may play a role in the development of these clusters. This article was authored by Natalia Koziyevkina, Yulia Vavchina, Natalia Voroneks and Chenko, and others.