 This study aimed to assess the impact of different programs on promoting seasonal influenza vaccination, SIV, uptake among health care workers, HCWs, in four teaching hospitals in Rome during the 2017 or 2018 season. The hospitals organized various strategies, including educational courses and dedicated units for influenza vaccination, with varying levels of success in promoting SIV uptake. The study found that easy access to the vaccination site was a key factor in determining higher vaccination coverage rates. This article was authored by Alessia Tognetto, by Malone Zorsely, Elisabetta Franco, and others.