 The study evaluated the immunogenicity and safety of an inactivated chromatographically purified varicelled-arrived Japanese encephalitis vaccine, CVIJE, in 152 healthy Thai children, with an average age of 14.4 months. All subjects had seroprotection after two doses and the seroprotection rates at one year were 89.3% with a geometric mean titer, GMT, of 49. Local and systemic reactions such as fever, vomiting, and poor appetite were noted within 28 days post-vaccination but were self-limited. The study concluded that CVIJE is safe, immunogenic, and provided high-neutralizing antibody titers. This article was authored by Pornthep Chantavanich, Kriangsaklim Kittakul, Chukiatsiravichayakul, and others.