 This study compared the impact of the COVID-19 pandemic on the lives of early career physicians and PhD researchers from underrepresented groups. It found that both groups experienced increased stress due to the pandemic, but physicians were more likely to be affected by clinical demands, research delays, and the potential for exposure to SARS-CoV-2. In contrast, PhD researchers were more likely to experience increased productivity, schedule flexibility, and quality time with friends and family. Future studies should focus on developing interventions to help these individuals cope with the effects of the pandemic. This article was offered by Jamie M. Doyle, Natalia E. Morwan, Chelsea N. Pru, and others.