 Balloon flower root, BFR, has been shown to contain bioactive compounds that exhibit anti-inflammatory, proliferative, and antioxidant properties. These compounds are contained within BFR-derived extracellular vesicles, BFR versus, which were found to be effective at reducing inflammation, promoting cell proliferation, and combating oxidative stress. This suggests that BFR versus may be used as a natural treatment option for chronic skin wounds caused by excessive reactive oxygen species, ROS. This article was authored by Mano Kim, Hyjin Jang, and Ju Hyun Park.